| Round | Pick | Team | Player | Overall Pick |
| 1 | 1 | Brawlers | Maurice Jones-Drew RB (JAC) | 1 |
| 1 | 2 | V-Tards | Steven Jackson RB (STL) | 2 |
| 1 | 3 | Benny's Boyz | Frank Gore RB (SF) | 3 |
| 1 | 4 | Shockers | Ladanian Tomlinson RB (SD) | 4 |
| 1 | 5 | Velociraptors | Drew Brees QB (NO) | 5 |
| 1 | 6 | Clams | Brian Westbrook RB (PHI) | 6 |
| 1 | 7 | Steamers | Larry Fitzgerald WR (ARI) | 7 |
| 1 | 8 | Breakhislegs | Brandon Jacobs RB (NYG) | 8 |
| 1 | 9 | Homers Heros | Clinton Portis RB (WAS) | 9 |
| 1 | 10 | Heavy Hitters | Randy Moss WR (NE) | 10 |
| 1 | 11 | Greenskins | Calvin Johnson WR (DET) | 11 |
| 1 | 12 | J-Men | Andre Johnson WR (HOU) | 12 |
| 2 | 1 | J-Men | Peyton Manning QB (IND) | 13 |
| 2 | 2 | Greenskins | Adrian Peterson RB (MIN) | 14 |
| 2 | 3 | Heavy Hitters | Reggie Wayne WR (IND) | 15 |
| 2 | 4 | Homers Heros | Tom Brady QB (NE) | 16 |
| 2 | 5 | Breakhislegs | Anquan Boldin WR (ARI) | 17 |
| 2 | 6 | Steamers | Greg Jennings WR (GB) | 18 |
| 2 | 7 | Clams | Tony Romo QB (DAL) | 19 |
| 2 | 8 | Velociraptors | Brandon Marshall WR (DEN) | 20 |
| 2 | 9 | Shockers | Marques Colston WR (NO) | 21 |
| 2 | 10 | Benny's Boyz | Kevin Smith RB (DET) | 22 |
| 2 | 11 | V-Tards | Thomas Jones RB (NYJ) | 23 |
| 2 | 12 | Brawlers | Ronnie Brown RB (MIA) | 24 |
| 3 | 1 | Brawlers | Jay Cutler QB (CHI) | 25 |
| 3 | 2 | V-Tards | Steve Smith WR (CAR) | 26 |
| 3 | 3 | Benny's Boyz | Donovan McNabb QB (PHI) | 27 |
| 3 | 4 | Shockers | Terrell Owens WR (DAL) | 28 |
| 3 | 5 | Velociraptors | Roy Williams WR (DAL) | 29 |
| 3 | 6 | Clams | Chad Ochocinco WR (CIN) | 30 |
| 3 | 7 | Steamers | Willie Parker RB (PIT) | 31 |
| 3 | 8 | Breakhislegs | Marion Barber RB (DAL) | 32 |
| 3 | 9 | Homers Heros | T.J. Houshmandzadeh WR (SEA) | 33 |
| 3 | 10 | Heavy Hitters | Matt Forte RB (Chi) | 34 |
| 3 | 11 | Greenskins | Marshawn Lynch RB (BUF) | 35 |
| 3 | 12 | J-Men | Jason Witten TE (DAL) | 36 |
| 4 | 1 | J-Men | Darren McFadden RB (Oak) | 37 |
| 4 | 2 | Greenskins | Aaron Rodgers QB (GB) | 38 |
| 4 | 3 | Heavy Hitters | Larry Johnson RB (KC) | 39 |
| 4 | 4 | Homers Heros | Joseph Addai RB (IND) | 40 |
| 4 | 5 | Breakhislegs | Carson Palmer QB (CIN) | 41 |
| 4 | 6 | Steamers | Derrick Ward RB (TB) | 42 |
| 4 | 7 | Clams | Lendale White RB (TEN) | 43 |
| 4 | 8 | Velociraptors | Tony Gonzalez TE (ATL) | 44 |
| 4 | 9 | Shockers | Jonathan Stewart RB (CAR) | 45 |
| 4 | 10 | Benny's Boyz | Roddy White WR (ATL) | 46 |
| 4 | 11 | V-Tards | Ben Roethlisberger QB (PIT) | 47 |
| 4 | 12 | Brawlers | Bernard Berrian WR (MIN) | 48 |
| 5 | 1 | Brawlers | Dallas Clark TE (IND) | 49 |
| 5 | 2 | V-Tards | Chris "Beanie" Wells RB (ARI) | 50 |
| 5 | 3 | Benny's Boyz | Reggie Bush RB (NO) | 51 |
| 5 | 4 | Shockers | Knowshon Moreno RB (DEN) | 52 |
| 5 | 5 | Velociraptors | Ray Rice RB (BAL) | 53 |
| 5 | 6 | Clams | DeAngelo Williams RB (CAR) | 54 |
| 5 | 7 | Steamers | Antonio Gates TE (SD) | 55 |
| 5 | 8 | Breakhislegs | Wes Welker WR (MIA) | 56 |
| 5 | 9 | Homers Heros | Jerricho Cotchery WR (NYJ) | 57 |
| 5 | 10 | Heavy Hitters | Jamal Lewis RB (CLE) | 58 |
| 5 | 11 | Greenskins | Glen Coffee RB (SF) "Reach much?" | 59 |
| 5 | 12 | J-Men | Desean Jackson WR (PHI) | 60 |
| 6 | 1 | J-Men | Donald Brown RB (IND) | 61 |
| 6 | 2 | Greenskins | Santana Moss WR (WAS) | 62 |
| 6 | 3 | Heavy Hitters | Devin Hester WR (CHI) | 63 |
| 6 | 4 | Homers Heros | Donald Driver WR (GB) | 64 |
| 6 | 5 | Breakhislegs | Tim Hightower RB (ARI) | 65 |
| 6 | 6 | Steamers | Darren Sproles RB (SD) | 66 |
| 6 | 7 | Clams | Hines Ward WR (PIT) | 67 |
| 6 | 8 | Velociraptors | Lee Evans WR (BUF) | 68 |
| 6 | 9 | Shockers | Laveranues Coles WR (NYJ) | 69 |
| 6 | 10 | Benny's Boyz | Anthony Gonzalez WR (IND) | 70 |
| 6 | 11 | V-Tards | Antonio Bryant | 71 |
| 6 | 12 | Brawlers | Laurence Maroney RB (NE) | 72 |
| 7 | 1 | Brawlers | Brett Favre QB (MIN) | 73 |
| 7 | 2 | V-Tards | Steelers DST (PIT) | 74 |
| 7 | 3 | Benny's Boyz | Dustin Keller TE (NYJ) | 75 |
| 7 | 4 | Shockers | Braylon Edwards WR (CLE) | 76 |
| 7 | 5 | Velociraptors | Steve Slaton RB (HOU) | 77 |
| 7 | 6 | Clams | Philip Rivers QB (SD) | 78 |
| 7 | 7 | Steamers | Chris Johnson RB (TEN) | 79 |
| 7 | 8 | Breakhislegs | Greg Olsen TE (CHI) | 80 |
| 7 | 9 | Homers Heros | Eli Manning QB (NYG) | 81 |
| 7 | 10 | Heavy Hitters | Felix Jones RB (DAL) | 82 |
| 7 | 11 | Greenskins | Chris Cooley TE (WAS) | 83 |
| 7 | 12 | J-Men | Ravens DST (BAL) | 84 |
| 8 | 1 | J-Men | Lance Moore WR (NO) | 85 |
| 8 | 2 | Greenskins | Chester Taylor RB (MIN) | 86 |
| 8 | 3 | Heavy Hitters | Matt Hasselback QB (SEA) | 87 |
| 8 | 4 | Homers Heros | Ahmad Bradshaw RB (NYG) | 88 |
| 8 | 5 | Breakhislegs | Kevin Walter WR (HOU) | 89 |
| 8 | 6 | Steamers | Willis McGahee RB (BAL) | 90 |
| 8 | 7 | Clams | Ted Ginn Jr. WR (MIA) | 91 |
| 8 | 8 | Velociraptors | Earnest Graham RB (TB) | 92 |
| 8 | 9 | Shockers | Lesean McCoy RB (PHI) | 93 |
| 8 | 10 | Benny's Boyz | Julius Jones RB (SEA) | 94 |
| 8 | 11 | V-Tards | Kyle Orton QB (DEN) | 95 |
| 8 | 12 | Brawlers | Santonio Holmes WR (PIT) | 96 |
| 9 | 1 | Brawlers | Dwayne Bowe WR (KC) | 97 |
| 9 | 2 | V-Tards | Derrick Mason WR (BAL) | 98 |
| 9 | 3 | Benny's Boyz | Giants DST (NYG) | 99 |
| 9 | 4 | Shockers | Vikings DST (MIN) | 100 |
| 9 | 5 | Velociraptors | Titans DST (TEN) | 101 |
| 9 | 6 | Clams | Ricky Williams RB (MIA) | 102 |
| 9 | 7 | Steamers | Torry Holt WR (JAC) | 103 |
| 9 | 8 | Breakhislegs | Matt Schaub QB (HOU) | 104 |
| 9 | 9 | Homers Heros | Eagles DST (PHI) | 105 |
| 9 | 10 | Heavy Hitters | Percy Harvin WR (MIN) | 106 |
| 9 | 11 | Greenskins | Leon Washington RB (NYJ) | 107 |
| 9 | 12 | J-Men | Rashard Mendenhall RB (PIT) | 108 |
| 10 | 1 | J-Men | Michael Turner RB (ATL) | 109 |
| 10 | 2 | Greenskins | Shonn Greene RB (NYJ) | 110 |
| 10 | 3 | Heavy Hitters | Kellen Winslow TE (CLE) | 111 |
| 10 | 4 | Homers Heros | Tony Scheffler TE (DEN) | 112 |
| 10 | 5 | Breakhislegs | Nate Washington WR (TEN) | 113 |
| 10 | 6 | Steamers | Trent Edwards QB (BUF) | 114 |
| 10 | 7 | Clams | John Carlson TE (SEA) | 115 |
| 10 | 8 | Velociraptors | Kevin Boss TE (NYG) | 116 |
| 10 | 9 | Shockers | Steve Breaston WR (ARI) | 117 |
| 10 | 10 | Benny's Boyz | Donnie Avery WR (STL) | 118 |
| 10 | 11 | V-Tards | Owen Daniels TE (HOU) | 119 |
| 10 | 12 | Brawlers | Bears DST (CHI) | 120 |
| 11 | 1 | Brawlers | Jeremy Maclin WR (PHI) | 121 |
| 11 | 2 | V-Tards | Matthew Stafford QB (DET) | 122 |
| 11 | 3 | Benny's Boyz | Mark Sanchez QB (NYJ) | 123 |
| 11 | 4 | Shockers | Joe Flacco QB (BAL) | 124 |
| 11 | 5 | Velociraptors | Brian Robiskie WR (CLE) | 125 |
| 11 | 6 | Clams | Josh Morgan WR (SF) | 126 |
| 11 | 7 | Steamers | Patriots DST (NE) | 127 |
| 11 | 8 | Breakhislegs | Jets DST (NYJ) | 128 |
| 11 | 9 | Homers Heros | Fred Taylor RB (JAC) | 129 |
| 11 | 10 | Heavy Hitters | Matt Ryan QB (ATL) | 130 |
| 11 | 11 | Greenskins | Domenik Hixon WR (NYG) | 131 |
| 11 | 12 | J-Men | Ryan Grant RB (GB) | 132 |
| 12 | 1 | J-Men | Jerious Norwood RB (ATL) | 133 |
| 12 | 2 | Greenskins | Redskins DST (WAS) | 134 |
| 12 | 3 | Heavy Hitters | Steve Smith WR (NYG) | 135 |
| 12 | 4 | Homers Heros | Fred Jackson RB (BUF) | 136 |
| 12 | 5 | Breakhislegs | Jason Campbell QB (WAS) | 137 |
| 12 | 6 | Steamers | Jeremy Shockey TE (NO) | 138 |
| 12 | 7 | Clams | Patrick Crayton WR (DAL) | 139 |
| 12 | 8 | Velociraptors | Jake Delhomme QB (CAR) | 140 |
| 12 | 9 | Shockers | Zach Miller TE (OAK) | 141 |
| 12 | 10 | Benny's Boyz | Cadillac Williams RB (TB) | 142 |
| 12 | 11 | V-Tards | Earl Bennett WR (CIN) | 143 |
| 12 | 12 | Brawlers | Chris Chambers WR (SD) | 144 |
| 13 | 1 | Brawlers | Correll Buckhalter RB (DEN) | 145 |
| 13 | 2 | V-Tards | Vincent Jackson WR (SD) | 146 |
| 13 | 3 | Benny's Boyz | Eddie Royal WR (DEN) | 147 |
| 13 | 4 | Shockers | Kurt Warner QB (ARI) | 148 |
| 13 | 5 | Velociraptors | Pierre Thomas RB (NO) | 149 |
| 13 | 6 | Clams | Dolphins DST (MIA) | 150 |
| 13 | 7 | Steamers | Matt Cassel QB (KC) | 151 |
| 13 | 8 | Breakhislegs | Stephen Gostkowski K (NE) | 152 |
| 13 | 9 | Homers Heros | Cedric Benson RB (CIN) | 153 |
| 13 | 10 | Heavy Hitters | Rob Bironas K (TEN) | 154 |
| 13 | 11 | Greenskins | Hakeem Nicks WR (NYG) | 155 |
| 13 | 12 | J-Men | Chris Henry WR (CIN) | 156 |
| 14 | 1 | J-Men | Brady Quinn QB (CLE) | 157 |
| 14 | 2 | Greenskins | David Garrard QB (JAC) | 158 |
| 14 | 3 | Heavy Hitters | Chargers DST (SD) | 159 |
| 14 | 4 | Homers Heros | Joey Galloway WR (TB) | 160 |
| 14 | 5 | Breakhislegs | Mushin Muhammad WR (CAR) | 161 |
| 14 | 6 | Steamers | Matt Leinart QB (ARI) | 162 |
| 14 | 7 | Clams | Mason Crosby K (GB) | 163 |
| 14 | 8 | Velociraptors | Le'Ron McClain RB (BAL) | 164 |
| 14 | 9 | Shockers | Ryan Longwell K (MIN) | 165 |
| 14 | 10 | Benny's Boyz | Jason Elam K (ATL) | 166 |
| 14 | 11 | V-Tards | David Akers K (PHI) | 167 |
| 14 | 12 | Brawlers | Nate Kaeding K (SD) | 168 |
| 15 | 1 | Brawlers | Michael Crabtree WR (SF) | 169 |
| 15 | 2 | V-Tards | Maurice Morris RB (SEA) | 170 |
| 15 | 3 | Benny's Boyz | Jamaal Charles RB (KC) | 171 |
| 15 | 4 | Shockers | Isaac Bruce WR (SF) | 172 |
| 15 | 5 | Velociraptors | Nick Folk K (DAL) | 173 |
| 15 | 6 | Clams | Panthers DST (CAR) | 174 |
| 15 | 7 | Steamers | Neil Rackers K (ARI) | 175 |
| 15 | 8 | Breakhislegs | Sammy Morris RB (NE) | 176 |
| 15 | 9 | Homers Heros | Robbie Gould K (CHI) | 177 |
| 15 | 10 | Heavy Hitters | Edgerrin James RB (SEA) | 178 |
| 15 | 11 | Greenskins | John Kasay K (CAR) | 179 |
| 15 | 12 | J-Men | John Carney AARP | 180 |