| Round | Pick | Team | Player | Overall Pick |
| 1 | 1 | Big Dnis | Adrian Peterson RB (MIN) | 1 |
| 1 | 2 | Breakhislegs | Maurice Jones-Drew RB (JAC) | 2 |
| 1 | 3 | Homers Heros | Drew Brees QB (NO) | 3 |
| 1 | 4 | Shockers | Frank Gore RB (SF) | 4 |
| 1 | 5 | Heavy Hitters | Steven Jackson RB (STL) | 5 |
| 1 | 6 | Vtards | Peyton Manning QB (IND) | 6 |
| 1 | 7 | DraftBusts | Andre Johnson WR (HOU) | 7 |
| 1 | 8 | Cleveland Steamers | Tony Romo QB (DAL) | 8 |
| 1 | 9 | Unicorn Colliders | Tom Brady QB (NE) | 9 |
| 1 | 10 | Southside Brawlers | Shonn Greene RB (NYJ) | 10 |
| 1 | 11 | J-Men | Randy Moss WR (NE) | 11 |
| 1 | 12 | Greenskins | Ryan Matthews RB (SD) | 12 |
| 2 | 1 | Greenskins | Aaron Rodgers QB (GB) | 13 |
| 2 | 2 | J-Men | Roddy White WR (ATL) | 14 |
| 2 | 3 | Southside Brawlers | Calvin Johnson WR (DET) | 15 |
| 2 | 4 | Unicorn Colliders | Ray Rice RB (Bal) | 16 |
| 2 | 5 | Cleveland Steamers | Larry Fitzgerald WR (ARI) | 17 |
| 2 | 6 | DraftBusts | Pierre Thomas RB (NO) | 18 |
| 2 | 7 | Vtards | Reggie Wayne WR (IND) | 19 |
| 2 | 8 | Heavy Hitters | Desean Jackson WR (PHI) | 20 |
| 2 | 9 | Shockers | Brandon Marshall WR (MIA) | 21 |
| 2 | 10 | Homers Heros | Greg Jennings WR (GB) | 22 |
| 2 | 11 | Breakhislegs | Steve Smith WR (CAR) | 23 |
| 2 | 12 | Big Dnis | DeAngelo Williams RB (CAR) | 24 |
| 3 | 1 | Big Dnis | Marques Colston WR (NO) | 25 |
| 3 | 2 | Breakhislegs | Anquan Boldin WR (BAL) | 26 |
| 3 | 3 | Homers Heros | Dwayne Bowe WR (KC) | 27 |
| 3 | 4 | Shockers | Beanie Wells RB (ARI) | 28 |
| 3 | 5 | Heavy Hitters | Wes Welker WR (NE) | 29 |
| 3 | 6 | Vtards | Jahvid Best RB (DET) | 30 |
| 3 | 7 | DraftBusts | Jay Cutler QB (CHI) | 31 |
| 3 | 8 | Cleveland Steamers | Marion Barber RB (DAL) | 32 |
| 3 | 9 | Unicorn Colliders | Percy Harvin WR (MIN) | 33 |
| 3 | 10 | Southside Brawlers | Joseph Addai RB (IND) | 34 |
| 3 | 11 | J-Men | Khowshon Moreno RB (DEN) | 35 |
| 3 | 12 | Greenskins | Antonio Gates TE (SD) | 36 |
| 4 | 1 | Greenskins | Malcolm Floyd WR (SD) | 37 |
| 4 | 2 | J-Men | Jermichael Finley TE (GB) | 38 |
| 4 | 3 | Southside Brawlers | Brett Favre QB (MIN) | 39 |
| 4 | 4 | Unicorn Colliders | Jeremy Maclin WR (PHI) | 40 |
| 4 | 5 | Cleveland Steamers | Chris Johnson RB (TEN) | 41 |
| 4 | 6 | DraftBusts | Matt Forte RB (CHI) | 42 |
| 4 | 7 | Vtards | Dallas Clark TE (IND) | 43 |
| 4 | 8 | Heavy Hitters | Ronnie Brown RB (MIA) | 44 |
| 4 | 9 | Shockers | Jason Witten TE (DAL) | 45 |
| 4 | 10 | Homers Heros | Brent Celek TE (PHI) | 46 |
| 4 | 11 | Breakhislegs | Jonathan Stewart RB (CAR) | 47 |
| 4 | 12 | Big Dnis | Phillip Rivers QB (SD) | 48 |
| 5 | 1 | Big Dnis | Chad Ochocinco WR (CIN) | 49 |
| 5 | 2 | Breakhislegs | Matt Schaub QB (HOU) | 50 |
| 5 | 3 | Homers Heros | Kevin Kolb QB (PHI) | 51 |
| 5 | 4 | Shockers | Lesean McCoy RB (PHI) | 52 |
| 5 | 5 | Heavy Hitters | Tony Gonzalez TE (ATL) | 53 |
| 5 | 6 | Vtards | Mike Wallace WWR (PIT) | 54 |
| 5 | 7 | DraftBusts | Arian Foster RB (HOU) | 55 |
| 5 | 8 | Cleveland Steamers | Chris Cooley TE (WAS) | 56 |
| 5 | 9 | Unicorn Colliders | Rashard Mendenhall RB (PIT) | 57 |
| 5 | 10 | Southside Brawlers | Owen Daniels TE (HOU) | 58 |
| 5 | 11 | J-Men | Joe Flacco QB (BAL) | 59 |
| 5 | 12 | Greenskins | Santana Moss WR (WAS) | 60 |
| 6 | 1 | Greenskins | Bernard Berrian WR (MIN) | 61 |
| 6 | 2 | J-Men | Michael Turner RB (ATL) | 62 |
| 6 | 3 | Southside Brawlers | Hines Ward WR (PIT) | 63 |
| 6 | 4 | Unicorn Colliders | Zach Miller TE (JAC) | 64 |
| 6 | 5 | Cleveland Steamers | Kellen Winslow TE (TB) | 65 |
| 6 | 6 | DraftBusts | Donald Driver WR (GB) | 66 |
| 6 | 7 | Vtards | Eli Manning QB (NYG) | 67 |
| 6 | 8 | Heavy Hitters | Cadillac Williams RB (TB) | 68 |
| 6 | 9 | Shockers | Robert Meachem WR (NO) | 69 |
| 6 | 10 | Homers Heros | Braylan Edwards WR (NYJ) | 70 |
| 6 | 11 | Breakhislegs | Jerome Harrison RB (CLE) | 71 |
| 6 | 12 | Big Dnis | Visanthe Shiancoe TE (MIN) | 72 |
| 7 | 1 | Big Dnis | John Carlson TE (SEA) | 73 |
| 7 | 2 | Breakhislegs | TJ Houshmandzadeh WR (SEA) | 74 |
| 7 | 3 | Homers Heros | Steve Breaston WR (ARI) | 75 |
| 7 | 4 | Shockers | Terrell Owens WR (CIN) | 76 |
| 7 | 5 | Heavy Hitters | Matt Ryan QB (ATL) | 77 |
| 7 | 6 | Vtards | Packers DST | 78 |
| 7 | 7 | DraftBusts | Jets DST | 79 |
| 7 | 8 | Cleveland Steamers | Carson Palmer QB (CIN) | 80 |
| 7 | 9 | Unicorn Colliders | Devin Aromashodu (CHI) | 81 |
| 7 | 10 | Southside Brawlers | Donovan McNabb QB (WAS) | 82 |
| 7 | 11 | J-Men | Ryan Grant RB (GB) | 83 |
| 7 | 12 | Greenskins | Clinton Portis RB (WAS) | 84 |
| 8 | 1 | Greenskins | Ryan Torrain RB (WAS) | 85 |
| 8 | 2 | J-Men | Ben Roethlisberger QB (PIT) | 86 |
| 8 | 3 | Southside Brawlers | Reggie Bush RB (NO) | 87 |
| 8 | 4 | Unicorn Colliders | Montario Hardesty RB (CLE) | 88 |
| 8 | 5 | Cleveland Steamers | Kenny Britt WR (TEN) | 89 |
| 8 | 6 | DraftBusts | Ahmad Bradshaw RB (NYG) | 90 |
| 8 | 7 | Vtards | Dez Bryant WR (DAL) | 91 |
| 8 | 8 | Heavy Hitters | Ladainian Tomlinson RB (NYJ) | 92 |
| 8 | 9 | Shockers | Steve Smith WR (NYG) | 93 |
| 8 | 10 | Homers Heros | Fred Jackson RB (BUF) | 94 |
| 8 | 11 | Breakhislegs | Ravens DST | 95 |
| 8 | 12 | Big Dnis | C.J. Spiller RB (BUF) | 96 |
| 9 | 1 | Big Dnis | Chad Henne QB (MIA) | 97 |
| 9 | 2 | Breakhislegs | Vince Young QB (TEN) | 98 |
| 9 | 3 | Homers Heros | Cedric Benson RB (CIN) | 99 |
| 9 | 4 | Shockers | Matthew Stafford QB (DET) | 100 |
| 9 | 5 | Heavy Hitters | Vikings DST | 101 |
| 9 | 6 | Vtards | Vincent Jackson WR (SD) | 102 |
| 9 | 7 | DraftBusts | Hakeem Nicks WR (NYG) | 103 |
| 9 | 8 | Cleveland Steamers | Brandon Jacobs RB (NYG) | 104 |
| 9 | 9 | Unicorn Colliders | Eagles DST | 105 |
| 9 | 10 | Southside Brawlers | Steelers DST | 106 |
| 9 | 11 | J-Men | Santonio Holmes WR (NYJ) | 107 |
| 9 | 12 | Greenskins | Cowboys DST | 108 |
| 10 | 1 | Greenskins | Sam Bradford QB (STL) | 109 |
| 10 | 2 | J-Men | 49ers DST | 110 |
| 10 | 3 | Southside Brawlers | Darren McFadden RB (OAK) | 111 |
| 10 | 4 | Unicorn Colliders | Alex Smith QB (SF) | 112 |
| 10 | 5 | Cleveland Steamers | Bears DST | 113 |
| 10 | 6 | DraftBusts | Lee Evans WR (BUF) | 114 |
| 10 | 7 | Vtards | Donald Brown RB (IND) | 115 |
| 10 | 8 | Heavy Hitters | Mike Williams WR (TB) | 116 |
| 10 | 9 | Shockers | Felix Jones RB (DAL) | 117 |
| 10 | 10 | Homers Heros | Cardinals DST | 118 |
| 10 | 11 | Breakhislegs | Justin Forsett RB (SEA) | 119 |
| 10 | 12 | Big Dnis | Patriots DST | 120 |
| 11 | 1 | Big Dnis | Laurent Robinson WR (STL) | 121 |
| 11 | 2 | Breakhislegs | Johnny Knox WR (CHI) | 122 |
| 11 | 3 | Homers Heros | Michael Bush RB (OAK) | 123 |
| 11 | 4 | Shockers | Saints DST | 124 |
| 11 | 5 | Heavy Hitters | Pierre Garcon WR (IND) | 125 |
| 11 | 6 | Vtards | Jamaal Charles RB (KC) | 126 |
| 11 | 7 | DraftBusts | Mike Sims-Walker WR (JAC) | 127 |
| 11 | 8 | Cleveland Steamers | Miles Austin WR (DAL) | 128 |
| 11 | 9 | Unicorn Colliders | Tony Scheffler TE (DET) | 129 |
| 11 | 10 | Southside Brawlers | Michael Crabtree WR (SF) | 130 |
| 11 | 11 | J-Men | Thomas Jones RB (KC) | 131 |
| 11 | 12 | Greenskins | Vernon Davis TE (SF) | 132 |
| 12 | 1 | Greenskins | Mohamed Massaquoi WR (CLE) | 133 |
| 12 | 2 | J-Men | Jabar Gafney WR (DEN) | 134 |
| 12 | 3 | Southside Brawlers | Derrick Mason WR (BAL) | 135 |
| 12 | 4 | Unicorn Colliders | Mario Manningham (NYG) | 136 |
| 12 | 5 | Cleveland Steamers | Austin Collie WR (IND) | 137 |
| 12 | 6 | DraftBusts | Ricky Williams RB (MIA) | 138 |
| 12 | 7 | Vtards | Garrett Hartley K (NO) | 139 |
| 12 | 8 | Heavy Hitters | Dexter McCluster WR (KC) | 140 |
| 12 | 9 | Shockers | Tim Hightower RB (ARI) | 141 |
| 12 | 10 | Homers Heros | Heath Miller TE (PIT) | 142 |
| 12 | 11 | Breakhislegs | Greg Olsen TE (CHI) | 143 |
| 12 | 12 | Big Dnis | Kareem Huggins RB (TB) | 144 |
| 13 | 1 | Big Dnis | Devin Hester WR (CHI) | 145 |
| 13 | 2 | Breakhislegs | Devery Henderson WR (NO) | 146 |
| 13 | 3 | Homers Heros | Bernard Scott RB (CIN) | 147 |
| 13 | 4 | Shockers | Dirty Sanchez QB (NYJ) | 148 |
| 13 | 5 | Heavy Hitters | Roy Williams WR (DAL) | 149 |
| 13 | 6 | Vtards | Toby Gerhart RB (MIN) | 150 |
| 13 | 7 | DraftBusts | Nate Kaeding K (SD) | 151 |
| 13 | 8 | Cleveland Steamers | Ryan Longwell K (MIN) | 152 |
| 13 | 9 | Unicorn Colliders | Legedu Naanee WR (SD) | 153 |
| 13 | 10 | Southside Brawlers | Steve Slaton RB (HOU) | 154 |
| 13 | 11 | J-Men | Leon Washington RB (SEA) | 155 |
| 13 | 12 | Greenskins | Sidney Rice WR (MIN) | 156 |
| 14 | 1 | Greenskins | Fred Davis TE (WAS) | 157 |
| 14 | 2 | J-Men | Stephen Gostkowski K (NE) | 158 |
| 14 | 3 | Southside Brawlers | Dustin Keller TE (NYJ) | 159 |
| 14 | 4 | Unicorn Colliders | Benjamin Watson TE (CLE) | 160 |
| 14 | 5 | Cleveland Steamers | Tim Tebow QB (DEN) | 161 |
| 14 | 6 | DraftBusts | Kevin Boss TE (NYG) | 162 |
| 14 | 7 | Vtards | Golden Tate WR (SEA) | 163 |
| 14 | 8 | Heavy Hitters | Mason Crosby K (GB) | 164 |
| 14 | 9 | Shockers | Julian Edelman WR (NE) | 165 |
| 14 | 10 | Homers Heros | Mardy Gilyard WR (STL) | 166 |
| 14 | 11 | Breakhislegs | Rob Bironas K (TEN) | 167 |
| 14 | 12 | Big Dnis | David Akers K (PHI) | 168 |
| 15 | 1 | Big Dnis | Willis McGahee RB (BAL) | 169 |
| 15 | 2 | Breakhislegs | Ben "never going to play a game in the NFL" Tate RB (HOU) | 170 |
| 15 | 3 | Homers Heros | Laurence Tynes K (NYG) | 171 |
| 15 | 4 | Shockers | Robbie Gould K (CHI) | 172 |
| 15 | 5 | Heavy Hitters | Matt Cassel QB (KC) | 173 |
| 15 | 6 | Vtards | Michael Hoofuckingtoolonglastname TE (STL) | 174 |
| 15 | 7 | DraftBusts | Kyle Orton QB (DEN) | 175 |
| 15 | 8 | Cleveland Steamers | Danario Alexander WR (SCLSU Mud Dogs) | 176 |
| 15 | 9 | Unicorn Colliders | Jay Feely K (ARI) | 177 |
| 15 | 10 | Southside Brawlers | Shane Graham K (BAL) | 178 |
| 15 | 11 | J-Men | Laurence Maroney RB (NE) | 179 |
| 15 | 12 | Greenskins | Larry Johnson RB (WAS) | 180 |